Anti-NUB1 antibody (566-615) (STJ94571)

Name: Anti-NUB1 antibody (566-615) (STJ94571)
SKU: STJ94571
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenThe antiserum was produced against synthesized peptide derived from human NYREN18. AA range:566-615

STJ94571

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Short Description	Rabbit polyclonal anti-NEDD8 ultimate buster 1 (566-615) for use in WB, IHC, IF and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC/IF/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Monkey
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	NUB1
Gene ID	51667
Uniprot ID	NUB1_HUMAN
Immunogen	The antiserum was produced against synthesized peptide derived from human NYREN18. AA range:566-615
Immunogen Region	566-615
Specificity	NUB1 Polyclonal Antibody detects endogenous levels of NUB1 protein.

Tissue Specificity	Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
Function	Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
Protein Name	Nedd8 Ultimate Buster 1 Negative Regulator Of Ubiquitin-Like Proteins 1 Renal Carcinoma Antigen Ny-Ren-18
Database Links	Reactome: R-HSA-8951664
Cellular Localisation	Nucleus Predominantly Nuclear
Alternative Antibody Names	Anti-Nedd8 Ultimate Buster 1 antibody Anti-Negative Regulator Of Ubiquitin-Like Proteins 1 antibody Anti-Renal Carcinoma Antigen Ny-Ren-18 antibody Anti-NUB1 antibody Anti-NYREN18 antibody

Information sourced from Uniprot.org