• Western blot analysis of lysates from MCF7 cells, using NTR1 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-NTSR1 antibody (181-230) (STJ94568)

SKU:
STJ94568

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Neurotensin receptor type 1 (181-230) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NTSR1
Gene ID: 4923
Uniprot ID: NTR1_HUMAN
Immunogen Region: 181-230
Specificity: NTR1 Polyclonal Antibody detects endogenous levels of NTR1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NTR1. AA range:181-230
Tissue Specificity Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.
Post Translational Modifications N-glycosylated. Palmitoylated.this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment.
Function G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis.
Protein Name Neurotensin Receptor Type 1
Nt-R-1
Ntr1
High-Affinity Levocabastine-Insensitive Neurotensin Receptor
Ntrh
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Membrane Raft
Palmitoylation Is Required For Localization At Cav1-Enriched Membrane Rafts
Alternative Antibody Names Anti-Neurotensin Receptor Type 1 antibody
Anti-Nt-R-1 antibody
Anti-Ntr1 antibody
Anti-High-Affinity Levocabastine-Insensitive Neurotensin Receptor antibody
Anti-Ntrh antibody
Anti-NTSR1 antibody
Anti-NTRR antibody

Information sourced from Uniprot.org

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