Anti-NTE antibody (Internal) (STJ71820)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-NTE (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave an approx 75kDa band in lysates of cell lines HeLa and Kelly after 2µg/ml antibody staining. Please note that currently we cannot find an explanation in th |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PNPLA6 |
| Gene ID | 10908 |
| Uniprot ID | PLPL6_HUMAN |
| Accession Number | NP_006693.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | YQGRQTSSIFEAAKQ |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. Hydrolyzes lysophospholipids and monoacylglycerols, preferring the 1-acyl to the 2-acyl isomer. Does not catalyze hydrolysis of di- or triacylglycerols or fatty acid amides. |
| Protein Name | Patatin-Like Phospholipase Domain-Containing Protein 6Neuropathy Target Esterase |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Antibody Names | Anti-Patatin-Like Phospholipase Domain-Containing Protein 6 antibodyAnti-Neuropathy Target Esterase antibodyAnti-PNPLA6 antibodyAnti-NTE antibody |
Information sourced from Uniprot.org