Anti-NSUN5 antibody (127-429) (STJ11100922)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NSUN5 (127-429) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NSUN5 |
| Gene ID | 55695 |
| Uniprot ID | NSUN5_HUMAN |
| Immunogen Region | 127-429 |
| Immunogen Sequence | RPGPASQLPRFVRVNTLKTC SDDVVDYFKRQGFSYQGRAS SLDDLRALKGKHFLLDPLMP ELLVFPAQTDLHEHPLYRAG HLILQDRASCLPAMLLDPPP GSHVIDACAAPGNKTSHLAA LLKNQGKIFAFDLDAKRLAS MATLLARAGVSCCELAEEDF LAVSPSDPRYHEVHYILLDP SCSGSGMPSRQLEEPGAGTP SPVRLHALAGFQQRALCHAL TFPSLQRLVYSTCSLCQEE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 127-429 of human NSUN5 (NP_060514.1). |
Additional Info
| Tissue Specificity | Ubiquitous. Detected in placenta, heart and skeletal muscle. |
| Function | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development. |
| Protein Name | 28s RrnaCytosine-C(5-MethyltransferaseNol1-Related ProteinNol1rNol1/Nop2/Sun Domain Family Member 5Williams-Beuren Syndrome Chromosomal Region 20a Protein |
| Database Links | |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-28s Rrna antibodyAnti-Cytosine-C(5-Methyltransferase antibodyAnti-Nol1-Related Protein antibodyAnti-Nol1r antibodyAnti-Nol1/Nop2/Sun Domain Family Member 5 antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 20a Protein antibodyAnti-NSUN5 antibodyAnti-NSUN5A antibodyAnti-WBSCR20 antibodyAnti-WBSCR20A antibody |
Information sourced from Uniprot.org