Anti-NSUN3 antibody (1-120) (STJ114758)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NSUN3 (1-120) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NSUN3 |
| Gene ID | 63899 |
| Uniprot ID | NSUN3_HUMAN |
| Immunogen Region | 1-120 |
| Immunogen Sequence | MLTQLKAKSEGKLAKQICKV VLDHFEKQYSKELGDAWNTV REILTSPSCWQYAVLLNRFN YPFELEKDLHLKGYHTLSQG SLPNYPKSVKCYLSRTPGRI PSERHQIGNLKKYYLLNAAS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human NSUN3 (NP_071355.1). |
Additional Info
| Function | Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt-tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5-formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation. |
| Protein Name | TrnaCytosine(34-C(5-Methyltransferase - MitochondrialNol1/Nop2/Sun Domain Family Member 3 |
| Database Links | |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Cytosine(34-C(5-Methyltransferase - Mitochondrial antibodyAnti-Nol1/Nop2/Sun Domain Family Member 3 antibodyAnti-NSUN3 antibodyAnti-MSTP077 antibodyAnti-UG0651E06 antibody |
Information sourced from Uniprot.org