Anti-nSMase antibody (STJA0037493)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenPeptide
General Information
| Short Description | Rabbit monoclonal anti-nSMase for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB-1:1000-1:5000IP-1:10-1:100 |
| Formulation | Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SMPD2 |
| Gene ID | 6610 |
| Uniprot ID | NSMA_HUMAN |
| Immunogen | Peptide |
Additional Info
| Function | Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo. Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine. |
| Protein Name | Sphingomyelin Phosphodiesterase 2Lyso-Platelet-Activating Factor-Phospholipase CLyso-Paf-PlcNeutral SphingomyelinaseN-SmaseNsmaseNsmase1 |
| Database Links | Reactome: R-HSA-193681Reactome: R-HSA-5626978Reactome: R-HSA-9840310 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingomyelin Phosphodiesterase 2 antibodyAnti-Lyso-Platelet-Activating Factor-Phospholipase C antibodyAnti-Lyso-Paf-Plc antibodyAnti-Neutral Sphingomyelinase antibodyAnti-N-Smase antibodyAnti-Nsmase antibodyAnti-Nsmase1 antibodyAnti-SMPD2 antibody |
Information sourced from Uniprot.org