Anti-NSF antibody (N-Term) (STJ13101440)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from n-terminal of human NSF conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and rat.
General Information
| Short Description | Rabbit polyclonal anti-NSF (N-Term) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A concentration of 10-50 ug/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | NSF |
| Gene ID | 4905 |
| Uniprot ID | NSF_HUMAN |
| Immunogen | A synthetic peptide from n-terminal of human NSF conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and rat. |
| Immunogen Region | N-Term |
| Specificity | Specific for NSF. |
Additional Info
| Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. |
| Protein Name | Vesicle-Fusing AtpaseN-Ethylmaleimide-Sensitive Fusion ProteinNem-Sensitive Fusion ProteinVesicular-Fusion Protein Nsf |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-416993Reactome: R-HSA-6807878Reactome: R-HSA-6811434Reactome: R-HSA-6811438Reactome: R-HSA-6811440 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Vesicle-Fusing Atpase antibodyAnti-N-Ethylmaleimide-Sensitive Fusion Protein antibodyAnti-Nem-Sensitive Fusion Protein antibodyAnti-Vesicular-Fusion Protein Nsf antibodyAnti-NSF antibody |
Information sourced from Uniprot.org