Host: |
Rabbit |
Applications: |
WB/IF/IP |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NSF (251-400) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:5000IF/ICC 1:50-1:200IP 1:1000-1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NSF |
Gene ID: |
4905 |
Uniprot ID: |
NSF_HUMAN |
Immunogen Region: |
251-400 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 251-400 of human NSF (NP_006169.2). |
Immunogen Sequence: |
KHVKGILLYGPPGCGKTLLA RQIGKMLNAREPKVVNGPEI LNKYVGESEANIRKLFADAE EEQRRLGANSGLHIIIFDEI DAICKQRGSMAGSTGVHDTV VNQLLSKIDGVEQLNNILVI GMTNRPDLIDEALLRPGRLE VKMEIGLPDE |
Post Translational Modifications | Phosphorylation at Ser-569 interferes with homohexamerization. |
Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. |
Protein Name | Vesicle-Fusing AtpaseN-Ethylmaleimide-Sensitive Fusion ProteinNem-Sensitive Fusion ProteinVesicular-Fusion Protein Nsf |
Database Links | Reactome: R-HSA-204005Reactome: R-HSA-416993Reactome: R-HSA-6807878Reactome: R-HSA-6811434Reactome: R-HSA-6811438Reactome: R-HSA-6811440 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Vesicle-Fusing Atpase antibodyAnti-N-Ethylmaleimide-Sensitive Fusion Protein antibodyAnti-Nem-Sensitive Fusion Protein antibodyAnti-Vesicular-Fusion Protein Nsf antibodyAnti-NSF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance