• Western blot of rat striatal lysate showing specific labeling of the ~75 kDa NSF protein.

Anti-NSF antibody (C-Term) (STJA0003730)

SKU:
STJA0003730-100

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Host: Rabbit
Applications: WB
Reactivity: Rat/Human/Non-Human Primates
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NSF (C-Term) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was antigen affinity purified from pooled serum.
Dilution Range: WB 1:1000
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Nsf
Gene ID: 60355
Uniprot ID: NSF_RAT
Immunogen Region: C-Term
Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Tissue Specificity Detected in brain (at protein level).
Post Translational Modifications Phosphorylation at Ser-569 interferes with homohexamerization.
Function Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling.
Protein Name Vesicle-Fusing Atpase
N-Ethylmaleimide-Sensitive Fusion Protein
Nem-Sensitive Fusion Protein
Vesicular-Fusion Protein Nsf
Database Links Reactome: R-RNO-204005
Reactome: -RNO-416993
Reactome: -RNO-6807878
Reactome: -RNO-6811434
Reactome: -RNO-6811438
Reactome: -RNO-6811440
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Vesicle-Fusing Atpase antibody
Anti-N-Ethylmaleimide-Sensitive Fusion Protein antibody
Anti-Nem-Sensitive Fusion Protein antibody
Anti-Vesicular-Fusion Protein Nsf antibody
Anti-Nsf antibody
Anti-Erg1 antibody

Information sourced from Uniprot.org

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