Anti-NSE antibody (416-433aa) [ZR406] (STJ180655)

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STJ180655
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Short Description :Rabbit monoclonal NSE (416-433aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :ZR406
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity purified
Dilution Range:1:100-200
Formulation:Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Storage Instruction:Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol:ENO2
Gene ID:2026
Uniprot ID:ENOG_HUMAN
Immunogen:A synthetic peptide corresponding to aa416-433 of human NSE gamma
Immunogen Region:416-433aa
Specificity:Positive Control: Pancreas or brain
Tissue Specificity The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Function Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
Protein Name Gamma-Enolase
2-Phospho-D-Glycerate Hydro-Lyase
Enolase 2
Neural Enolase
Neuron-Specific Enolase
Nse
Database Links Reactome: R-HSA-70171
Reactome: R-HSA-70263
Cellular Localisation Cytoplasm
Cell Membrane
Can Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form
Alternative Antibody Names Anti-Gamma-Enolase antibody
Anti-2-Phospho-D-Glycerate Hydro-Lyase antibody
Anti-Enolase 2 antibody
Anti-Neural Enolase antibody
Anti-Neuron-Specific Enolase antibody
Anti-Nse antibody
Anti-ENO2 antibody

Information sourced from Uniprot.org