Anti-NSD3 antibody (383-660aa) [AT7B4] (STJA0041522)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant human NSD3 (383-660aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-NSD3 (383-660aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT7B4 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NSD3 |
| Gene ID | 54904 |
| Uniprot ID | NSD3_HUMAN |
| Accession Number | NP_075447 |
| Immunogen | Recombinant human NSD3 (383-660aa) purified from E. coli |
| Immunogen Region | 383-660aa |
Additional Info
| Tissue Specificity | Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. |
| Function | Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. |
| Protein Name | Histone-Lysine N-Methyltransferase Nsd3Nuclear Set Domain-Containing Protein 3Protein WhistleWhsc1-Like 1 Isoform 9 With Methyltransferase Activity To LysineWolf-Hirschhorn Syndrome Candidate 1-Like Protein 1Whsc1-Like Protein 1 |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Nsd3 antibodyAnti-Nuclear Set Domain-Containing Protein 3 antibodyAnti-Protein Whistle antibodyAnti-Whsc1-Like 1 Isoform 9 With Methyltransferase Activity To Lysine antibodyAnti-Wolf-Hirschhorn Syndrome Candidate 1-Like Protein 1 antibodyAnti-Whsc1-Like Protein 1 antibodyAnti-NSD3 antibodyAnti-WHSC1L1 antibodyAnti-DC28 antibody |
Information sourced from Uniprot.org