• Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-NRIP1 antibody (STJA0010137)

SKU:
STJA0010137

$62.10 - $305.10
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Nuclear receptor-interacting protein 1 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-p 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NRIP1
Gene ID: 8204
Uniprot ID: NRIP1_HUMAN
Specificity: This antibody detects endogenous levels of Human, Mouse, Rat RIP140
Immunogen: Synthesized peptide derived from human RIP140
Post Translational Modifications Acetylation regulates its nuclear translocation and corepressive activity. Acetylation abolishes interaction with CTBP1. Phosphorylation enhances interaction with YWHAH.
Function Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function. Plays a role in renal development.
Protein Name Nuclear Receptor-Interacting Protein 1
Nuclear Factor Rip140
Receptor-Interacting Protein 140
Database Links Reactome: R-HSA-3899300
Reactome: R-HSA-400253
Reactome: R-HSA-9018519
Reactome: R-HSA-9029558
Reactome: R-HSA-9632974
Reactome: R-HSA-9707616
Cellular Localisation Nucleus
Localized To Discrete Foci And Redistributes To Larger Nuclear Domains Upon Binding To Ligand-Bound Nr3c1
Alternative Antibody Names Anti-Nuclear Receptor-Interacting Protein 1 antibody
Anti-Nuclear Factor Rip140 antibody
Anti-Receptor-Interacting Protein 140 antibody
Anti-NRIP1 antibody

Information sourced from Uniprot.org

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