Anti-NRG4 antibody (11-60 aa) (STJ192544)

SKU:
STJ192544
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Pro-neuregulin-4, membrane-bound isoform (11-60 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:NRG4
Gene ID:145957
Uniprot ID:NRG4_HUMAN
Immunogen:Synthesized peptide derived from the human protein at the amino acid range 11-60
Immunogen Region:11-60 aa
Specificity:NRG4 Polyclonal Antibody detects endogenous levels of protein.
Function Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors.
Protein Name Pro-Neuregulin-4 - Membrane-Bound Isoform
Pro-Nrg4 Cleaved Into - Neuregulin-4
Nrg-4
Database Links Reactome: R-HSA-1227986
Reactome: R-HSA-1236394
Reactome: R-HSA-1250196
Reactome: R-HSA-1250342
Reactome: R-HSA-1250347
Reactome: R-HSA-1251985
Reactome: R-HSA-1257604
Reactome: R-HSA-1963640
Reactome: R-HSA-1963642
Reactome: R-HSA-2219530
Reactome: R-HSA-5673001
Reactome: R-HSA-6785631
Reactome: R-HSA-6811558
Reactome: R-HSA-8847993
Reactome: R-HSA-8863795
Reactome: R-HSA-9664565
Reactome: R-HSA-9665686
Cellular Localisation Pro-Neuregulin-4
Membrane-Bound Isoform: Cell Membrane
Single-Pass Type I Membrane Protein
Does Not Seem To Be Active
Neuregulin-4: Secreted
Alternative Antibody Names Anti-Pro-Neuregulin-4 - Membrane-Bound Isoform antibody
Anti-Pro-Nrg4 Cleaved Into - Neuregulin-4 antibody
Anti-Nrg-4 antibody
Anti-NRG4 antibody

Information sourced from Uniprot.org