Anti-NREP antibody (13-62 aa) (STJ94874)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human C5orf13 at the amino acid range 13-62
General Information
| Short Description | Rabbit polyclonal anti-Neuronal regeneration-related protein (13-62 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NREP |
| Gene ID | 9315 |
| Uniprot ID | NREP_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human C5orf13 at the amino acid range 13-62 |
| Immunogen Region | 13-62 aa |
| Specificity | P311 Polyclonal Antibody detects endogenous levels of P311 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on Ser-59. Phosphorylation decreases stability and activity. |
| Function | May have roles in neural function. Ectopic expression augments motility of gliomas. Also promotes axonal regeneration. May also have functions in cellular differentiation. Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. |
| Protein Name | Neuronal Regeneration-Related ProteinNeuronal Protein 3.1Protein P311 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Neuronal Regeneration-Related Protein antibodyAnti-Neuronal Protein 3.1 antibodyAnti-Protein P311 antibodyAnti-NREP antibodyAnti-C5orf13 antibodyAnti-P311 antibody |
Information sourced from Uniprot.org