Anti-NR4A2 antibody (Internal Region) (STJA0005792)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acids from an internal sequence of the human Nurr1 protein
General Information
| Short Description | Rabbit polyclonal anti-Nurr1 (Internal Region) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Antigen Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | PBS + 0.02% NaN3 |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NR4A2 |
| Gene ID | 4929 |
| Uniprot ID | NR4A2_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acids from an internal sequence of the human Nurr1 protein |
| Immunogen Region | Internal Region |
| Specificity | Reacts with an internal sequence of the human Nurr1 protein. Also reacts with rat and mouse Nurr1. |
Additional Info
| Function | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. |
| Protein Name | Nuclear Receptor Subfamily 4 Group A Member 2Immediate-Early Response Protein NotOrphan Nuclear Receptor Nurr1Transcriptionally-Inducible Nuclear Receptor |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-4090294 |
| Cellular Localisation | CytoplasmNucleusMostly NuclearOxidative Stress Promotes Cytoplasmic Localization |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 4 Group A Member 2 antibodyAnti-Immediate-Early Response Protein Not antibodyAnti-Orphan Nuclear Receptor Nurr1 antibodyAnti-Transcriptionally-Inducible Nuclear Receptor antibodyAnti-NR4A2 antibodyAnti-NOT antibodyAnti-NURR1 antibodyAnti-TINUR antibody |
Information sourced from Uniprot.org