| Tissue Specificity | Predominantly expressed in liver. |
| Post Translational Modifications | Phosphorylated at Thr-38 by PKC, dephosphorylation of Thr-38 is required for nuclear translocation and activation. |
| Function | Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. |
| Protein Name | Nuclear Receptor Subfamily 1 Group I Member 3Constitutive Activator Of Retinoid ResponseConstitutive Active ResponseConstitutive Androstane ReceptorCarOrphan Nuclear Receptor Mb67 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonRecruited To The Cytoplasm By Dnajc7 |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 1 Group I Member 3 antibodyAnti-Constitutive Activator Of Retinoid Response antibodyAnti-Constitutive Active Response antibodyAnti-Constitutive Androstane Receptor antibodyAnti-Car antibodyAnti-Orphan Nuclear Receptor Mb67 antibodyAnti-NR1I3 antibodyAnti-CAR antibody |
Information sourced from Uniprot.org
