• Immunohistochemistry analysis of paraffin-embedded mouse kidney using MATK antibody (STJ28734) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat kidney using MATK antibody (STJ28734) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of THP-1 cells, using MATK antibody (STJ28734) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-MATK antibody (352-466) (STJ28734)

SKU:
STJ28734

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MATK (352-466) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MATK
Gene ID: 4145
Uniprot ID: MATK_HUMAN
Immunogen Region: 352-466
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1).
Immunogen Sequence: PEALKHGKFTSKSDVWSFGV LLWEVFSYGRAPYPKMSLKE VSEAVEKGYRMEPPEGCPGP VHVLMSSCWEAEPARRPPFR KLAEKLARELRSAGAPASVS GQDADGSTSPRSQEP
Tissue Specificity Expressed in various myeloid cell lines, detected in brain and lung.
Function Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Protein Name Megakaryocyte-Associated Tyrosine-Protein Kinase
Csk Homologous Kinase
Chk
Hematopoietic Consensus Tyrosine-Lacking Kinase
Protein Kinase Hyl
Tyrosine-Protein Kinase Ctk
Database Links Reactome: R-HSA-8863795
Cellular Localisation Cytoplasm
Membrane
In Platelets
90% Of Matk Localizes To The Membrane Fraction
And Translocates To The Cytoskeleton Upon Thrombin Stimulation
Alternative Antibody Names Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibody
Anti-Csk Homologous Kinase antibody
Anti-Chk antibody
Anti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibody
Anti-Protein Kinase Hyl antibody
Anti-Tyrosine-Protein Kinase Ctk antibody
Anti-MATK antibody
Anti-CTK antibody
Anti-HYL antibody

Information sourced from Uniprot.org

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