| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nuclear receptor subfamily 1 group I member 3 (71-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NR1I3 |
| Gene ID: |
9970 |
| Uniprot ID: |
NR1I3_HUMAN |
| Immunogen Region: |
71-120 aa |
| Specificity: |
MB67 Polyclonal Antibody detects endogenous levels of MB67 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human NR1I3 at the amino acid range 71-120 |
| Post Translational Modifications | Phosphorylated at Thr-38 by PKC, dephosphorylation of Thr-38 is required for nuclear translocation and activation. |
| Function | Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. |
| Protein Name | Nuclear Receptor Subfamily 1 Group I Member 3Constitutive Activator Of Retinoid ResponseConstitutive Active ResponseConstitutive Androstane ReceptorCarOrphan Nuclear Receptor Mb67 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonRecruited To The Cytoplasm By Dnajc7 |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 1 Group I Member 3 antibodyAnti-Constitutive Activator Of Retinoid Response antibodyAnti-Constitutive Active Response antibodyAnti-Constitutive Androstane Receptor antibodyAnti-Car antibodyAnti-Orphan Nuclear Receptor Mb67 antibodyAnti-NR1I3 antibodyAnti-CAR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
