Anti-NR0B1/DAX1 antibody (STJA0037898)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human DAX1
General Information
| Short Description | Rabbit monoclonal anti-NR0B1/DAX1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NR0B1 |
| Gene ID | 190 |
| Uniprot ID | NR0B1_HUMAN |
| Immunogen | A synthesized peptide derived from human DAX1 |
Additional Info
| Function | Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency. |
| Protein Name | Nuclear Receptor Subfamily 0 Group B Member 1Dss-Ahc Critical Region On The X Chromosome Protein 1Nuclear Receptor Dax-1 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Cytoplasm And NucleusHomodimers Exits In The Cytoplasm And In The Nucleus |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 0 Group B Member 1 antibodyAnti-Dss-Ahc Critical Region On The X Chromosome Protein 1 antibodyAnti-Nuclear Receptor Dax-1 antibodyAnti-NR0B1 antibodyAnti-AHC antibodyAnti-DAX1 antibody |
Information sourced from Uniprot.org