Immunofluorescence of mouse tissue with Anti-NPR2 primary antibody (STJ502456). Green: Grueneberg ganglion neurons. Red: Antibody immunoreactivity. Blue: Nuclei. Staining is found on blood vessel walls.

Anti-NPR2 antibody (C-Term) (STJ502456)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein.
STJ502456-100
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General Information

Short DescriptionRabbit polyclonal antibody anti-NPR2 (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
ApplicationsCM/ELISA/ICC/IF/IHC/IP/WB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.75-1.20 ยตg/ยตl
PurificationAffinity Purified
Dilution RangeWB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:200
ICC: 1:200
IF: 1:50-1:200
CFM: 1:200
FormulationContains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage InstructionStore at-20ยฐC for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolNPR2
Gene ID4882
Uniprot IDANPRB_HUMAN
ImmunogenSynthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein.
Immunogen RegionC-Term

Additional Info

Post Translational Modifications Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated.
Function Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
Protein Name Atrial Natriuretic Peptide Receptor 2
Atrial Natriuretic Peptide Receptor Type B
Anp-B
Anpr-B
Npr-B
Guanylate Cyclase B
Gc-B
Database Links Reactome: R-HSA-5578768
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Atrial Natriuretic Peptide Receptor 2 antibody
Anti-Atrial Natriuretic Peptide Receptor Type B antibody
Anti-Anp-B antibody
Anti-Anpr-B antibody
Anti-Npr-B antibody
Anti-Guanylate Cyclase B antibody
Anti-Gc-B antibody
Anti-NPR2 antibody
Anti-ANPRB antibody

Information sourced from Uniprot.org

Citations

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