Anti-NPR2 antibody (130-320) (STJ118501)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NPR2 (130-320) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NPR2 |
| Gene ID | 4882 |
| Uniprot ID | ANPRB_HUMAN |
| Immunogen Region | 130-320 |
| Immunogen Sequence | SAKNDHYRTLVRTGPSAPKL GEFVVTLHGHFNWTARAALL YLDARTDDRPHYFTIEGVFE ALQGSNLSVQHQVYAREPGG PEQATHFIRANGRIVYICGP LEMLHEILLQAQRENLTNGD YVFFYLDVFGESLRAGPTRA TGRPWQDNRTREQAQALREA FQTVLVITYREPPNPEYQEF QNRLLIRARED |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 130-320 of human ANPRB/NRP2 (NP_003986.2). |
Additional Info
| Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
| Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
| Protein Name | Atrial Natriuretic Peptide Receptor 2Atrial Natriuretic Peptide Receptor Type BAnp-BAnpr-BNpr-BGuanylate Cyclase BGc-B |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Atrial Natriuretic Peptide Receptor 2 antibodyAnti-Atrial Natriuretic Peptide Receptor Type B antibodyAnti-Anp-B antibodyAnti-Anpr-B antibodyAnti-Npr-B antibodyAnti-Guanylate Cyclase B antibodyAnti-Gc-B antibodyAnti-NPR2 antibodyAnti-ANPRB antibody |
Information sourced from Uniprot.org