Anti-NPHS2/SRN1 antibody (C-Term) (STJ73014)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-NPHS2/SRN1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 42-45kDa band observed in Human and Mouse Kidney lysates (calculated MW of 42.2kDa according to Human NP_055440.1 and Mouse NP_569723.1). Recommended concentration: 0.5-2µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | NPHS2 |
| Gene ID | 7827 |
| Uniprot ID | PODO_HUMAN |
| Accession Number | NP_055440.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | SPSKPVEPLNPKK |
Additional Info
| Post Translational Modifications | Isoform 2: Glycosylated. |
| Function | Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. |
| Protein Name | Podocin |
| Database Links | Reactome: R-HSA-373753 |
| Cellular Localisation | Isoform 1: Cell MembranePeripheral Membrane ProteinIsoform 2: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Podocin antibodyAnti-NPHS2 antibody |
Information sourced from Uniprot.org