Anti-NPHS2 antibody [R03-3V9] (STJA0036642)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human NPHS2
General Information
| Short Description | Rabbit monoclonal anti-NPHS2 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-3V9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NPHS2 |
| Gene ID | 7827 |
| Uniprot ID | PODO_HUMAN |
| Immunogen | A synthesized peptide derived from human NPHS2 |
Additional Info
| Tissue Specificity | Almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli. |
| Post Translational Modifications | Isoform 2: Glycosylated. |
| Function | Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. |
| Protein Name | Podocin |
| Database Links | Reactome: R-HSA-373753 |
| Cellular Localisation | Isoform 1: Cell MembranePeripheral Membrane ProteinIsoform 2: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Podocin antibodyAnti-NPHS2 antibody |
Information sourced from Uniprot.org