| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nephrocystin-3 (1092-1142 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NPHP3 |
| Gene ID: |
27031 |
| Uniprot ID: |
NPHP3_HUMAN |
| Immunogen Region: |
1092-1142 aa |
| Specificity: |
This antibody detects endogenous levels of NPHP3 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human NPHP3 at the amino acid range 1092-1142 |
| Function | Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements. |
| Protein Name | Nephrocystin-3 |
| Database Links | Reactome: R-HSA-5624138 |
| Cellular Localisation | Cell ProjectionCiliumLocalization To Cilium Is Mediated Via Interaction With Unc119 And Unc119bWhich Bind To The Myristoyl Moiety Of The N-Terminus |
| Alternative Antibody Names | Anti-Nephrocystin-3 antibodyAnti-NPHP3 antibodyAnti-KIAA2000 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
