Anti-NOXA1 antibody (STJ193133)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-NADPH oxidase activator 1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NOXA1 |
| Gene ID | 10811 |
| Uniprot ID | NOXA1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | NOXA1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Interaction with YWHAZ depends on phosphorylation by PKA. |
| Function | Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. |
| Protein Name | Nadph Oxidase Activator 1Nox Activator 1Antigen Ny-Co-31Ncf2-Like ProteinP67phox-Like FactorP51-Nox |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
| Cellular Localisation | CytoplasmCell MembraneTranslocation To Membranes Depends On Noxo1 Or Ncf1 And Maybe Rac1 |
| Alternative Antibody Names | Anti-Nadph Oxidase Activator 1 antibodyAnti-Nox Activator 1 antibodyAnti-Antigen Ny-Co-31 antibodyAnti-Ncf2-Like Protein antibodyAnti-P67phox-Like Factor antibodyAnti-P51-Nox antibodyAnti-NOXA1 antibodyAnti-P51NOX antibody |
Information sourced from Uniprot.org