Anti-NOX1 antibody (200-300) (STJ114195)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NOX1 (200-300) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NOX1 |
| Gene ID | 27035 |
| Uniprot ID | NOX1_HUMAN |
| Immunogen Region | 200-300 |
| Immunogen Sequence | YFEVFWYTHHLFIFYILGLG IHGIGGIVRGQTEESMNESH PRKCAESFEMWDDRDSHCRR PKFEGHPPESWKWILAPVIL YICERILRFYRSQQKVVITK V |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NOX1 (NP_008983.2). |
Additional Info
| Tissue Specificity | Isoform NOH-1L: Detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. |
| Post Translational Modifications | Phosphorylation at Thr-430 mediated by PKC/PRKBC positively regulates its interaction with NOXA1 and enzyme activity. |
| Function | NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. Isoform NOH-1L: NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. |
| Protein Name | Nadph Oxidase 1Nox-1Mitogenic Oxidase 1Mox-1Nadh/Nadph Mitogenic Oxidase Subunit P65-MoxNoh-1 |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
| Cellular Localisation | Cell ProjectionInvadopodium MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Nadph Oxidase 1 antibodyAnti-Nox-1 antibodyAnti-Mitogenic Oxidase 1 antibodyAnti-Mox-1 antibodyAnti-Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox antibodyAnti-Noh-1 antibodyAnti-NOX1 antibodyAnti-MOX1 antibodyAnti-NOH1 antibody |
Information sourced from Uniprot.org