Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NOSTRIN (270-430) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NOSTRIN |
Gene ID: |
115677 |
Uniprot ID: |
NOSTN_HUMAN |
Immunogen Region: |
270-430 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 270-430 of human NOSTRIN (NP_001034813.2). |
Immunogen Sequence: |
ILSTENKSEFLLTDYFEEDP NSAMDKERRKSLLKPKLLRL QRDIEKASKDKEGLERMLKT YSSTSSFSDAKSQKDTAALM DENNLKLDLLEANSYKLSSM LAELEQRPQPSHPCSNSIFR WREKEHTHSYVKISRPFLMK RLENIVSKASSGGQSNPGSS T |
Tissue Specificity | Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over-expressed in placenta from women with pre-eclampsia (at protein level). |
Function | Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. |
Protein Name | NostrinBm247 HomologNitric Oxide Synthase Traffic InducerNitric Oxide Synthase TraffickerEnos-Trafficking Inducer |
Database Links | Reactome: R-HSA-203641 |
Cellular Localisation | Isoform 1: Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic VesicleCytoplasmCytoskeletonEnriched In Selected Actin StructuresIsoform 3: Nucleus |
Alternative Antibody Names | Anti-Nostrin antibodyAnti-Bm247 Homolog antibodyAnti-Nitric Oxide Synthase Traffic Inducer antibodyAnti-Nitric Oxide Synthase Trafficker antibodyAnti-Enos-Trafficking Inducer antibodyAnti-NOSTRIN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance