Anti-NOS1 antibody (N-Term) (STJA0005670)

Name: Anti-NOS1 antibody (N-Term) (STJA0005670)
SKU: STJA0005670-100
Price: 488.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthetic peptide corresponding to amino acids from the N-terminal region of the human variant of neuronal nitric oxide synthase (nNOS)

STJA0005670-100

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Short Description	Rabbit polyclonal anti-nNOS (N-Term) for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Purification	Antigen Affinity Purified
Dilution Range	WB 1:500-1:1000
Formulation	PBS + 0.02% NaN3
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	NOS1
Gene ID	4842
Uniprot ID	NOS1_HUMAN
Immunogen	Synthetic peptide corresponding to amino acids from the N-terminal region of the human variant of neuronal nitric oxide synthase (nNOS)
Immunogen Region	N-Term
Specificity	Reacts with the N-terminal region of the human variant of nitric oxide synthase (NOS). The neuronal form of NOS (nNOS) is one of three forms and is enzymatically active as a dimer.

Post Translational Modifications	Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Function	Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Protein Name	Nitric Oxide Synthase 1 Constitutive Nos Nc-Nos Nos Type I Neuronal Nos N-Nos Nnos Nitric Oxide Synthase - Brain Bnos Peptidyl-Cysteine S-Nitrosylase Nos1
Database Links	Reactome: R-HSA-1222556 Reactome: R-HSA-392154 Reactome: R-HSA-5578775
Cellular Localisation	Cell Membrane Sarcolemma Peripheral Membrane Protein Cell Projection Dendritic Spine In Skeletal Muscle It Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein Complex In Neurons Enriched In Dendritic Spines
Alternative Antibody Names	Anti-Nitric Oxide Synthase 1 antibody Anti-Constitutive Nos antibody Anti-Nc-Nos antibody Anti-Nos Type I antibody Anti-Neuronal Nos antibody Anti-N-Nos antibody Anti-Nnos antibody Anti-Nitric Oxide Synthase - Brain antibody Anti-Bnos antibody Anti-Peptidyl-Cysteine S-Nitrosylase Nos1 antibody Anti-NOS1 antibody

Information sourced from Uniprot.org