Anti-NOS1 antibody (C-Term) (STJA0005498)

SKU:
STJA0005498-100

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Host: Rabbit
Applications: WB/ICC/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-nNOS (C-Term) is suitable for use in Western Blot, Immunocytochemistry and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Purification: Antigen Affinity Purified
Dilution Range: WB 1:1000
IHC 1:300
ICC 1:200
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NOS1
Gene ID: 4842
Uniprot ID: NOS1_HUMAN
Immunogen Region: C-Term
Specificity: The antibody detects a 155 kDa* protein on SDS-PAGE immunoblots of rat and mouse brain tissue lysates, as well in the rat pituitary cell line GC.
Immunogen: Amino acid residues within the C-terminal region of human nNOS. This human nNOS sequence has high homology with similar regions in rat and mouse nNOS.
Post Translational Modifications Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Function Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Protein Name Nitric Oxide Synthase 1
Constitutive Nos
Nc-Nos
Nos Type I
Neuronal Nos
N-Nos
Nnos
Nitric Oxide Synthase - Brain
Bnos
Peptidyl-Cysteine S-Nitrosylase Nos1
Database Links Reactome: R-HSA-1222556
Reactome: R-HSA-392154
Reactome: R-HSA-5578775
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cell Projection
Dendritic Spine
In Skeletal Muscle
It Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein Complex
In Neurons
Enriched In Dendritic Spines
Alternative Antibody Names Anti-Nitric Oxide Synthase 1 antibody
Anti-Constitutive Nos antibody
Anti-Nc-Nos antibody
Anti-Nos Type I antibody
Anti-Neuronal Nos antibody
Anti-N-Nos antibody
Anti-Nnos antibody
Anti-Nitric Oxide Synthase - Brain antibody
Anti-Bnos antibody
Anti-Peptidyl-Cysteine S-Nitrosylase Nos1 antibody
Anti-NOS1 antibody

Information sourced from Uniprot.org

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