Anti-NOS1 antibody (C-Term) (STJ70096)

Name: Anti-NOS1 antibody (C-Term) (STJ70096)
SKU: STJ70096-100
Price: 312.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostGoat

ConjugationUnconjugated

IsotypeIgG

STJ70096-100

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Short Description	Goat polyclonal antibody anti-NOS1 (C-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications.
Applications	Pep-ELISA/WB/IHC/IF/FC
Host	Goat
Reactivity	Human/Mouse/Rat/Dog/Cow
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.5 mg/mL
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range	Peptide ELISA: antibody detection limit dilution 1:128000. WB: Approx. 160kDa band observed in Mouse Brain lysates (calculated MW of 160.5kDa according to NP_032738.1). Recommended concentration: 1-2µg/ml. Primary incubation 1 hour at room temper
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction	Store at-20°C on receipt and minimise freeze-thaw cycles.

Post Translational Modifications	Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Function	Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Protein Name	Nitric Oxide Synthase 1 Constitutive Nos Nc-Nos Nos Type I Neuronal Nos N-Nos Nnos Nitric Oxide Synthase - Brain Bnos Peptidyl-Cysteine S-Nitrosylase Nos1
Database Links	Reactome: R-HSA-1222556 Reactome: R-HSA-392154 Reactome: R-HSA-5578775
Cellular Localisation	Cell Membrane Sarcolemma Peripheral Membrane Protein Cell Projection Dendritic Spine In Skeletal Muscle It Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein Complex In Neurons Enriched In Dendritic Spines
Alternative Antibody Names	Anti-Nitric Oxide Synthase 1 antibody Anti-Constitutive Nos antibody Anti-Nc-Nos antibody Anti-Nos Type I antibody Anti-Neuronal Nos antibody Anti-N-Nos antibody Anti-Nnos antibody Anti-Nitric Oxide Synthase - Brain antibody Anti-Bnos antibody Anti-Peptidyl-Cysteine S-Nitrosylase Nos1 antibody Anti-NOS1 antibody

Information sourced from Uniprot.org