Anti-NOLC1 antibody [SRM13156] (STJ11107886)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Nucleolar And Coiled-Body Phosphoprotein 1 antibody for use in WB, IHC-P, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13156 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:1000-1:6000IHC-P, 1:50-1:200IF/ICC, 1:50-1:200ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NOLC1 |
| Gene ID | 9221 |
| Uniprot ID | NOLC1_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Function | Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. |
| Protein Name | Nucleolar And Coiled-Body Phosphoprotein 1140 Kda Nucleolar PhosphoproteinNopp140Hepatitis C Virus Ns5a-Transactivated Protein 13Hcv Ns5a-Transactivated Protein 13Nucleolar 130 Kda ProteinNucleolar Phosphoprotein P130 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusCytoplasmShuttles Between The Nucleolus And The CytoplasmAt Telophase It Begins To Assemble Into Granular-Like Pre-Nucleolar Bodies Which Are Subsequently Relocated To Nucleoli At The Early G1-Phase |
| Alternative Antibody Names | Anti-Nucleolar And Coiled-Body Phosphoprotein 1 antibodyAnti-140 Kda Nucleolar Phosphoprotein antibodyAnti-Nopp140 antibodyAnti-Hepatitis C Virus Ns5a-Transactivated Protein 13 antibodyAnti-Hcv Ns5a-Transactivated Protein 13 antibodyAnti-Nucleolar 130 Kda Protein antibodyAnti-Nucleolar Phosphoprotein P130 antibodyAnti-NOLC1 antibodyAnti-KIAA0035 antibodyAnti-NS5ATP13 antibody |
Information sourced from Uniprot.org