Anti-NOL8 antibody (1118-1167) (STJ94530)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NOL8. AA range:1118-1167
General Information
| Short Description | Rabbit polyclonal anti-Nucleolar protein 8 (1118-1167) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NOL8 |
| Gene ID | 55035 |
| Uniprot ID | NOL8_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NOL8. AA range:1118-1167 |
| Immunogen Region | 1118-1167 |
| Specificity | Nop132 Polyclonal Antibody detects endogenous levels of Nop132 protein. |
Additional Info
| Tissue Specificity | Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle. |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. |
| Protein Name | Nucleolar Protein 8Nucleolar Protein Nop132 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusLocalizes In The Nucleolar-Organizing Region During Ribosome Biogenesis |
| Alternative Antibody Names | Anti-Nucleolar Protein 8 antibodyAnti-Nucleolar Protein Nop132 antibodyAnti-NOL8 antibodyAnti-C9orf34 antibodyAnti-NOP132 antibody |
Information sourced from Uniprot.org