• Western blot analysis of lysates from MCF-7 cells, using NOC2L Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-NOC2L antibody (602-651) (STJ94525)

SKU:
STJ94525

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Nucleolar complex protein 2 homolog (602-651) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NOC2L
Gene ID: 26155
Uniprot ID: NOC2L_HUMAN
Immunogen Region: 602-651
Specificity: NOC2L Polyclonal Antibody detects endogenous levels of NOC2L protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651
Function Acts as an inhibitor of histone acetyltransferase activity.prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.
Protein Name Nucleolar Complex Protein 2 Homolog
Protein Noc2 Homolog
Noc2-Like Protein
Novel Inhat Repressor
Database Links Reactome: R-HSA-6804756
Cellular Localisation Nucleus
Nucleoplasm
Nucleolus
Translocates From The Nucleoli To The Nucleoplasm In Presence Of Several Stressors Like Ultraviolet Irradiation And Actinomycin-D
Predominantly Detected In The Nucleoli In Non-Mitotic Cells
Predominantly Detected In Nucleoplasma In Cells Undergoing Mitosis
Alternative Antibody Names Anti-Nucleolar Complex Protein 2 Homolog antibody
Anti-Protein Noc2 Homolog antibody
Anti-Noc2-Like Protein antibody
Anti-Novel Inhat Repressor antibody
Anti-NOC2L antibody
Anti-NIR antibody

Information sourced from Uniprot.org

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