Anti-NMU/Neuromedin-U antibody [SAA1777] (STJA0020205)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Neuromedin-U Cleaved Into-Neuromedin Precursor-Related Peptide 36 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1777 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | NMU |
| Gene ID | 10874 |
| Uniprot ID | NMU_HUMAN |
Additional Info
| Function | Neuromedin-U-25: Ligand for receptors NMUR1 and NMUR2. Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder. Neuromedin precursor-related peptide 33: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release although its potency is much lower than that of neuromedin precursor-related peptide 36. Neuromedin precursor-related peptide 36: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system. |
| Protein Name | Neuromedin-U Cleaved Into - Neuromedin Precursor-Related Peptide 36Nurp36 - Neuromedin Precursor-Related Peptide 33Nurp33 - Neuromedin-U-25Nmu-25 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neuromedin-U Cleaved Into - Neuromedin Precursor-Related Peptide 36 antibodyAnti-Nurp36 - Neuromedin Precursor-Related Peptide 33 antibodyAnti-Nurp33 - Neuromedin-U-25 antibodyAnti-Nmu-25 antibodyAnti-NMU antibody |
Information sourced from Uniprot.org