Anti-NMT1 antibody (1-250) (STJ111389)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NMT1 (1-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NMT1 |
| Gene ID | 4836 |
| Uniprot ID | NMT1_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MADESETAVKPPAPPLPQMM EGNGNGHEHCSDCENEEDNS YNRGGLSPANDTGAKKKKKK QKKKKEKGSETDSAQDQPVK MNSLPAERIQEIQKAIELFS VGQGPAKTMEEASKRSYQFW DTQPVPKLGEVVNTHGPVEP DKDNIRQEPYTLPQGFTWDA LDLGDRGVLKELYTLLNENY VEDDDNMFRFDYSPEFLLWA LRPPGWLPQWHCGVRVVSSR KLVGFISAIPANIHIYDTE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NMT1 (NP_066565.1). |
Additional Info
| Tissue Specificity | Heart, gut, kidney, liver and placenta. |
| Function | Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle. |
| Protein Name | Glycylpeptide N-Tetradecanoyltransferase 1Myristoyl-Coa -Protein N-Myristoyltransferase 1Hsnmt1Nmt 1Type I N-MyristoyltransferasePeptide N-Myristoyltransferase 1Protein-Lysine Myristoyltransferase Nmt1 |
| Database Links | Reactome: R-HSA-162599Reactome: R-HSA-203615Reactome: R-HSA-2514859Reactome: R-HSA-75108 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCopurifies With Ribosomes |
| Alternative Antibody Names | Anti-Glycylpeptide N-Tetradecanoyltransferase 1 antibodyAnti-Myristoyl-Coa -Protein N-Myristoyltransferase 1 antibodyAnti-Hsnmt1 antibodyAnti-Nmt 1 antibodyAnti-Type I N-Myristoyltransferase antibodyAnti-Peptide N-Myristoyltransferase 1 antibodyAnti-Protein-Lysine Myristoyltransferase Nmt1 antibodyAnti-NMT1 antibodyAnti-NMT antibody |
Information sourced from Uniprot.org