• Western blot analysis of various lysates using NME8 Rabbit polyclonal antibody (STJ11102862) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-NME8 antibody (299-588) (STJ11102862)

SKU:
STJ11102862

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NME8 (299-588) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NME8
Gene ID: 51314
Uniprot ID: TXND3_HUMAN
Immunogen Region: 299-588
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 299-588 of human NME8 (NP_057700.3).
Immunogen Sequence: FMDAFFPDFKKMKSMKLEKT LALLRPNLFHERKDDVLRII KDEDFKILEQRQVVLSEKEA QALCKEYENEDYFNKLIENM TSGPSLALVLLRDNGLQYWK QLLGPRTVEEAIEYFPESLC AQFAMDSLPVNQLYGSDSLE TAEREIQHFFPLQSTLGLIK PHATSEQREQILKIVKEAGF DLTQVKKMFLTPEQIEKIYP KVTGKDFYKDLLEMLSVGPS MVMILTKWNAVAEWRRLMG
Tissue Specificity Testis-specific. Expressed only in primary spermatocytes and round spermatids.
Function Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.
Protein Name Thioredoxin Domain-Containing Protein 3
Nm23-H8
Nme/Nm23 Family Member 8
Spermatid-Specific Thioredoxin-2
Sptrx-2
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Thioredoxin Domain-Containing Protein 3 antibody
Anti-Nm23-H8 antibody
Anti-Nme/Nm23 Family Member 8 antibody
Anti-Spermatid-Specific Thioredoxin-2 antibody
Anti-Sptrx-2 antibody
Anti-NME8 antibody
Anti-SPTRX2 antibody
Anti-TXNDC3 antibody

Information sourced from Uniprot.org

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