Anti-NME5 antibody (STJA0004393)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human NME5
General Information
| Short Description | Rabbit polyclonal anti-Nucleoside Diphosphate Kinase Homolog 5 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.8 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NME5 |
| Gene ID | 8382 |
| Uniprot ID | NDK5_HUMAN |
| Immunogen | Recombinant protein of human NME5 |
Additional Info
| Tissue Specificity | Specifically expressed in testis germinal cells. |
| Function | Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia. Does not seem to have nucleoside diphosphate kinase (NDPK) activity. Confers protection from cell death by BAX and alters the cellular levels of several antioxidant enzymes including GPX5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. Exhibits a 3'-5' exonuclease activity with a preference for single-stranded DNA, suggesting roles in DNA proofreading and repair. |
| Protein Name | Nucleoside Diphosphate Kinase Homolog 5Ndk-H 5Ndp Kinase Homolog 53'-5' Exonuclease Nme5Inhibitor Of P53-Induced Apoptosis-BetaIpia-BetaTestis-Specific Nm23 HomologNm23-H5 |
| Database Links | |
| Cellular Localisation | Cell ProjectionCiliumCytoplasmCytoskeletonFlagellum Axoneme |
| Alternative Antibody Names | Anti-Nucleoside Diphosphate Kinase Homolog 5 antibodyAnti-Ndk-H 5 antibodyAnti-Ndp Kinase Homolog 5 antibodyAnti-3'-5' Exonuclease Nme5 antibodyAnti-Inhibitor Of P53-Induced Apoptosis-Beta antibodyAnti-Ipia-Beta antibodyAnti-Testis-Specific Nm23 Homolog antibodyAnti-Nm23-H5 antibodyAnti-NME5 antibody |
Information sourced from Uniprot.org