Anti-NME5 antibody (25-75 aa) (STJ197724)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NDK5 at the amino acid range 25-75
General Information
| Short Description | Rabbit polyclonal anti-Nucleoside diphosphate kinase homolog 5 (25-75 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NME5 |
| Gene ID | 8382 |
| Uniprot ID | NDK5_HUMAN |
| Immunogen | Synthesized peptide derived from the human NDK5 at the amino acid range 25-75 |
| Immunogen Region | 25-75 aa |
| Specificity | This antibody detects endogenous levels of human NDK5 |
Additional Info
| Function | Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia. Does not seem to have nucleoside diphosphate kinase (NDPK) activity. Confers protection from cell death by BAX and alters the cellular levels of several antioxidant enzymes including GPX5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. Exhibits a 3'-5' exonuclease activity with a preference for single-stranded DNA, suggesting roles in DNA proofreading and repair. |
| Protein Name | Nucleoside Diphosphate Kinase Homolog 5Ndk-H 5Ndp Kinase Homolog 53'-5' Exonuclease Nme5Inhibitor Of P53-Induced Apoptosis-BetaIpia-BetaTestis-Specific Nm23 HomologNm23-H5 |
| Database Links | |
| Cellular Localisation | Cell ProjectionCiliumCytoplasmCytoskeletonFlagellum Axoneme |
| Alternative Antibody Names | Anti-Nucleoside Diphosphate Kinase Homolog 5 antibodyAnti-Ndk-H 5 antibodyAnti-Ndp Kinase Homolog 5 antibodyAnti-3'-5' Exonuclease Nme5 antibodyAnti-Inhibitor Of P53-Induced Apoptosis-Beta antibodyAnti-Ipia-Beta antibodyAnti-Testis-Specific Nm23 Homolog antibodyAnti-Nm23-H5 antibodyAnti-NME5 antibody |
Information sourced from Uniprot.org