| Host: |
Mouse |
| Applications: |
IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Homeobox protein Nkx-3.1 (1-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ABT267 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
Liquid in PBS pH7.2, 0.03% Proclin 300, with stabilizing protein. |
| Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: |
IHC-P 1:200-400WB 1:200-1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NKX3-1 |
| Gene ID: |
4824 |
| Uniprot ID: |
NKX31_HUMAN |
| Immunogen Region: |
1-100 aa |
| Specificity: |
The antibody can specifically recognize human NKX3.1 protein. |
| Immunogen: |
Synthesized peptide derived from the human NKX3.1 at the amino acid range 1-100 |
| Post Translational Modifications | Ubiquitinated by TOPORS.monoubiquitinated at several residues and also polyubiquitinated on single residues. |
| Function | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGTAG-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. |
| Protein Name | Homeobox Protein Nkx-3.1Homeobox Protein Nk-3 Homolog A |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Nkx-3.1 antibodyAnti-Homeobox Protein Nk-3 Homolog A antibodyAnti-NKX3-1 antibodyAnti-NKX3.1 antibodyAnti-NKX3A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
