| Short Description : | Rabbit monoclonal anti-NKX2.2 for use in IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P/ICC/IF |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R05-5E5 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Chromatography |
| Dilution Range: | IHC 1:50-1:100IF 1:50-1:200 |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | NKX2-2 |
| Gene ID: | 4821 |
| Uniprot ID: | NKX22_HUMAN |
| Immunogen: | A synthesized peptide derived from human NKX2.2 |
| Function | Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas. May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter. |
| Protein Name | Homeobox Protein Nkx-2.2Homeobox Protein Nk-2 Homolog B |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210746 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Nkx-2.2 antibodyAnti-Homeobox Protein Nk-2 Homolog B antibodyAnti-NKX2-2 antibodyAnti-NKX2.2 antibodyAnti-NKX2B antibody |
Information sourced from Uniprot.org
