Anti-NKX2-2 antibody (200-273) {Biotin} (STJ501931)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenC-epitope synthetic peptide taken within amino acid region 200-273 on human homeobox protein Nkx-2.2
General Information
| Short Description | Rabbit polyclonal antibody anti-NKX2-2 (200-273) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.68-0.70 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:4, 000ELISA: 1:4, 000IP: 1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NKX2-2 |
| Gene ID | 4821 |
| Uniprot ID | NKX22_HUMAN |
| Immunogen | C-epitope synthetic peptide taken within amino acid region 200-273 on human homeobox protein Nkx-2.2 |
| Immunogen Region | 200-273 |
Additional Info
| Function | Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas. May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter. |
| Protein Name | Homeobox Protein Nkx-2.2Homeobox Protein Nk-2 Homolog B |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210746 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Nkx-2.2 antibodyAnti-Homeobox Protein Nk-2 Homolog B antibodyAnti-NKX2-2 antibodyAnti-NKX2.2 antibodyAnti-NKX2B antibody |
Information sourced from Uniprot.org