| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NF-kappa-B inhibitor-interacting Ras-like protein 1 (50-130 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NKIRAS1 |
| Gene ID: |
28512 |
| Uniprot ID: |
KBRS1_HUMAN |
| Immunogen Region: |
50-130 aa |
| Specificity: |
KBRS1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 50-130 |
| Function | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. |
| Protein Name | Nf-Kappa-B Inhibitor-Interacting Ras-Like Protein 1I-Kappa-B-Interacting Ras-Like Protein 1Kappa B-Ras Protein 1Kappab-Ras1 |
| Database Links | Reactome: R-HSA-1810476Reactome: R-HSA-445989Reactome: R-HSA-933542 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Nf-Kappa-B Inhibitor-Interacting Ras-Like Protein 1 antibodyAnti-I-Kappa-B-Interacting Ras-Like Protein 1 antibodyAnti-Kappa B-Ras Protein 1 antibodyAnti-Kappab-Ras1 antibodyAnti-NKIRAS1 antibodyAnti-KBRAS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
