Anti-NIPSNAP2 antibody (STJA0009524)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human GBAS
General Information
| Short Description | Rabbit polyclonal anti-Protein NipSnap homolog 2 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NIPSNAP2 |
| Gene ID | 2631 |
| Uniprot ID | NIPS2_HUMAN |
| Immunogen | Synthesized peptide derived from human GBAS |
| Specificity | This antibody detects endogenous levels of GBAS at Human |
Additional Info
| Function | Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria. Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2). |
| Protein Name | Protein Nipsnap Homolog 2Nipsnap2Glioblastoma-Amplified Sequence |
| Database Links | Reactome: R-HSA-9013407Reactome: R-HSA-9013409 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Protein Nipsnap Homolog 2 antibodyAnti-Nipsnap2 antibodyAnti-Glioblastoma-Amplified Sequence antibodyAnti-NIPSNAP2 antibodyAnti-GBAS antibody |
Information sourced from Uniprot.org