Anti-NINJ2 antibody (STJA0008521)

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	NINJ2
Gene ID:	4815
Uniprot ID:	NINJ2_HUMAN
Specificity:	This antibody detects endogenous levels of NINJ2 at Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from human NINJ2

Function	Effector of necroptotic and pyroptotic programmed cell death that mediates plasma membrane rupture (cytolysis). Acts downstream of Gasdermin (GSDMA, GSDMB, GSDMC, GSDMD, or GSDME) or MLKL during pyroptosis or necroptosis, respectively: oligomerizes in response to death stimuli and promotes plasma membrane rupture by introducing hydrophilic faces of 2 alpha helices into the hydrophobic membrane, leading to release intracellular molecules named damage-associated molecular patterns (DAMPs) that propagate the inflammatory response. Also acts as a homophilic transmembrane adhesion molecule involved in nerve regeneration. Promotes axonal growth.
Protein Name	Ninjurin-2 Nerve Injury-Induced Protein 2
Cellular Localisation	Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Ninjurin-2 antibody Anti-Nerve Injury-Induced Protein 2 antibody Anti-NINJ2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance