Anti-NHERF2 antibody (20-100 aa) (STJ97629)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from NHERF-2 at the amino acid range 20-100
General Information
| Short Description | Rabbit polyclonal anti-Na+/H+ exchange regulatory cofactor NHE-RF2 (20-100 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NHERF2 |
| Gene ID | 9351 |
| Uniprot ID | NHRF2_HUMAN |
| Immunogen | Synthesized peptide derived from NHERF-2 at the amino acid range 20-100 |
| Immunogen Region | 20-100 aa |
| Specificity | NHERF-2 Polyclonal Antibody detects endogenous levels of NHERF-2 protein. |
Additional Info
| Function | Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. |
| Protein Name | Na(+/H(+ Exchange Regulatory Cofactor Nhe-Rf2Nherf-2Nhe3 Kinase A Regulatory Protein E3karpSry-Interacting Protein 1Sip-1Sodium-Hydrogen Exchanger Regulatory Factor 2Solute Carrier Family 9 Isoform A3 Regulatory Factor 2Tyrosine Kinase Activator Protein 1Tka-1 |
| Database Links | |
| Cellular Localisation | Endomembrane SystemPeripheral Membrane ProteinNucleusApical Cell MembraneLocalizes With Ezr And Podxl At The Apical Cell Membrane Of Glomerular Epithelium Cells And The Sides Of The Food ProcessesNuclearIn A Punctate Pattern |
| Alternative Antibody Names | Anti-Na(+/H(+ Exchange Regulatory Cofactor Nhe-Rf2 antibodyAnti-Nherf-2 antibodyAnti-Nhe3 Kinase A Regulatory Protein E3karp antibodyAnti-Sry-Interacting Protein 1 antibodyAnti-Sip-1 antibodyAnti-Sodium-Hydrogen Exchanger Regulatory Factor 2 antibodyAnti-Solute Carrier Family 9 Isoform A3 Regulatory Factor 2 antibodyAnti-Tyrosine Kinase Activator Protein 1 antibodyAnti-Tka-1 antibodyAnti-NHERF2 antibodyAnti-SLC9A3R2 antibody |
Information sourced from Uniprot.org