| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-NGFRAP1 (C-Term) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
BEX3 |
| Gene ID: |
27018 |
| Uniprot ID: |
BEX3_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_996800.1; NP_996798.1; NP_055195.1 |
| Specificity: |
This antibody is expected to recognise isoform a (NP_996800.1) and isoform b (NP_996798.1 and NP_055195.1). |
| Immunogen Sequence: |
CLRILMGELSNHHDH |
| Post Translational Modifications | Ubiquitinated. Degraded by the proteasome. |
| Function | May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. |
| Protein Name | Protein Bex3Brain-Expressed X-Linked Protein 3Nerve Growth Factor Receptor-Associated Protein 1Ovarian Granulosa Cell 13.0 Kda Protein Hgr74P75ntr-Associated Cell Death Executor |
| Database Links | Reactome: R-HSA-205025 |
| Cellular Localisation | NucleusCytoplasmCytosolShuttles Between The Cytoplasm And The NucleusAssociates With Replicating Mitochondria |
| Alternative Antibody Names | Anti-Protein Bex3 antibodyAnti-Brain-Expressed X-Linked Protein 3 antibodyAnti-Nerve Growth Factor Receptor-Associated Protein 1 antibodyAnti-Ovarian Granulosa Cell 13.0 Kda Protein Hgr74 antibodyAnti-P75ntr-Associated Cell Death Executor antibodyAnti-BEX3 antibodyAnti-DXS6984E antibodyAnti-NADE antibodyAnti-NGFRAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
