Anti-NFRKB antibody (370-495) [S5255RM] (STJ11105255)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Nuclear Factor Related To Kappa-B-Binding Protein (370-495) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5255RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NFRKB |
| Gene ID | 4798 |
| Uniprot ID | NFRKB_HUMAN |
| Immunogen Region | 370-495 |
| Immunogen Sequence | LGINEISSSFFSLLLEILLL ESQASLPMLEERVLDWQSSP ASSLNSWFSAAPNWAELVLP ALQYLAGESRAVPSSFSPFV EFKEKTQQWKLLGQSQDNEK ELAALFQLWLETKDQAFCKQ ENEDSS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 370-495 of human NFRKB (NP_001137307.1). |
Additional Info
| Tissue Specificity | Expressed in thymus, brain, testes, spleen and liver. |
| Function | Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex. |
| Protein Name | Nuclear Factor Related To Kappa-B-Binding ProteinDna-Binding Protein R Kappa-BIno80 Complex Subunit G |
| Database Links | Reactome: R-HSA-5689603Reactome: R-HSA-5696394 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Factor Related To Kappa-B-Binding Protein antibodyAnti-Dna-Binding Protein R Kappa-B antibodyAnti-Ino80 Complex Subunit G antibodyAnti-NFRKB antibodyAnti-INO80G antibody |
Information sourced from Uniprot.org