| Host: |
Rabbit |
| Applications: |
WB/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nuclear factor interleukin-3-regulated protein (61-110 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NFIL3 |
| Gene ID: |
4783 |
| Uniprot ID: |
NFIL3_HUMAN |
| Immunogen Region: |
61-110 aa |
| Specificity: |
E4BP4 Polyclonal Antibody detects endogenous levels of E4BP4 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human NFIL3 at the amino acid range 61-110 |
| Function | Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-GATTACTGTAACT-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death. Represses the transcription of CYP2A5. Positively regulates the expression and activity of CES2 by antagonizing the repressive action of NR1D1 on CES2. Required for the development of natural killer cell precursors. |
| Protein Name | Nuclear Factor Interleukin-3-Regulated ProteinE4 Promoter-Binding Protein 4Interleukin-3 Promoter Transcriptional ActivatorInterleukin-3-Binding Protein 1Transcriptional Activator Nf-Il3a |
| Database Links | Reactome: R-HSA-400253 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Factor Interleukin-3-Regulated Protein antibodyAnti-E4 Promoter-Binding Protein 4 antibodyAnti-Interleukin-3 Promoter Transcriptional Activator antibodyAnti-Interleukin-3-Binding Protein 1 antibodyAnti-Transcriptional Activator Nf-Il3a antibodyAnti-NFIL3 antibodyAnti-E4BP4 antibodyAnti-IL3BP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
