Anti-NFASC antibody (830-1100) (STJ24750)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NFASC (830-1100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NFASC |
| Gene ID | 23114 |
| Uniprot ID | NFASC_HUMAN |
| Immunogen Region | 830-1100 |
| Immunogen Sequence | RFRVRQPNLETINLEWDHPE HPNGIMIGYTLKYVAFNGTK VGKQIVENFSPNQTKFTVQR TDPVSRYRFTLSARTQVGSG EAVTEESPAPPNEATPTAAP PTLPPTTVGATGAVSSTDAT AIAATTEATTVPIIPTVAPT TIATTTTVATTTTTTAAATT TTESPPTTTSGTKIHESAPD EQSIWNVTVLPNSKWANITW KHNFGPGTDFVVEYIDSNHT KKTVPVKAQAQPIQLTDLY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 830-1100 of human NFASC (NP_001005388.2). |
Additional Info
| Function | Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. |
| Protein Name | Neurofascin |
| Database Links | Reactome: R-HSA-445095Reactome: R-HSA-447043Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 8: Cell JunctionParanodal Septate Junction |
| Alternative Antibody Names | Anti-Neurofascin antibodyAnti-NFASC antibodyAnti-KIAA0756 antibody |
Information sourced from Uniprot.org