| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Neurofibromin (1551-1600) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NF1 |
| Gene ID: |
4763 |
| Uniprot ID: |
NF1_HUMAN |
| Immunogen Region: |
1551-1600 |
| Specificity: |
Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600 |
| Tissue Specificity | Detected in brain, peripheral nerve, lung, colon and muscle. |
| Function | Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity. |
| Protein Name | NeurofibrominNeurofibromatosis-Related Protein Nf-1 Cleaved Into - Neurofibromin Truncated |
| Database Links | Reactome: R-HSA-5658442Reactome: R-HSA-6802953 |
| Cellular Localisation | NucleusNucleolusCell Membrane |
| Alternative Antibody Names | Anti-Neurofibromin antibodyAnti-Neurofibromatosis-Related Protein Nf-1 Cleaved Into - Neurofibromin Truncated antibodyAnti-NF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
